PR INTERNATIONAL
E-mail here E-Mail Web Address

REGULATIONS / RESEARCH / XENOGENIC CLINICS / CLINICIANS / LINKS
Categorised in order of importance towards study

Xenogenically : Porcine to Human - United Kingdom Regulations: United Kingdom Xenotransplantation Regulatory Authority (UKXIRA), established in 1997 then disbanded in December 2006. The safety and efficacy of xenotransplantation clinical trials is now to be assessed by the Medicines Healthcare Products Regulatory Agency and ethically reviewed by "Local Research Ethics Committees" (LRECs); experimental treatments are assessed by each Trust's, "Clinical Governance Committee" (CGC), and experimental research by an LREC.

“Investigators considering offering experimental treatment outside a research framework are encouraged to take public health issues and long‐term health surveillance of patients into account.”

The experimenters in xenotransplantation are only encouraged, not required, to consider the very issues that are the source of legitimate ethical (and legal) concern. Meaning the moratorium suspension was lifted to permit investigation for potentially clinically viable use in the UK
Web: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2598150/
Xenogenically : Porcine to Human - Xenogeneic Transplantation without PERV Infection : Diabetes Research Group, King's College London, United Kingdom : Co-Encapsulation of Islets with Mesenchymal Stem Cells Improves Islet Function Web: https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(16)36220-7
Xenogenically : Porcine to Human - Xenogeneic Transplantation without PERV Infection : No PERV infection was detected in any of the patients from whom sufficient DNA was extracted to allow complete PCR analysis (XEN 111 Study Group - Search for cross-species transmission of porcine endogenous retrovirus in patients treated with living pig tissue) Web: https://www.ncbi.nlm.nih.gov/pubmed/10455044/
Xenogenically : Porcine to Human - Xenogeneic Transplantation without PERV Infection : No evidence of pig DNA or retroviral infection in patients with short-term extracorporeal connection to pig kidneys. Web: https://www.ncbi.nlm.nih.gov/pubmed/9728987/
Xenogenically : Porcine to Human - Xenotransplantation in using living pig cells - Professor Bob Elliott: Living Cell Technologies (encapsulated porcine islet cells) porcine has proven in infectivity studies Intracorporeal and Extracorporeal safety. No evidence of human infection with PERV has been documented in patients exposed to pig tissue, in spite of the presence of long-term PERV microchimerism in some patients info@lctglobal.com
Web: https://www.sciencelearn.org.nz/videos/484-pig-cell-transplants-and-perv
Web: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC88959/
Web: https://en.wikipedia.org/wiki/Cell_encapsulation
Xenogenically : Porcine to Human - Xeno Virology: Dr Joachim Denner : - CRISPR slices virus genes out of pigs: CRISPR "knocks out" PERV genes at all 62 sites in the pig genome, all appeared to be PERV-free. Web: https://www.sciencemag.org/news/2017/08/crispr-slices-virus-genes-out-pigs-will-it-make-organ-transplants-humans-safer
Xenogenically : Porcine to Human - Xeno Virology: Dr Joachim Denner : Robert Koch Institut DennerJ@rki.de. Dr Joachim Denner advised detecting the presence of PERV genomic RNA viral proteins by Reverse Transcription-Polymerase Chain Reaction (RT-PCR) Western blot analysis using specific sera against p15E and gp70. When asking Professor Robin Weiss, MD who discovered PERV in 1997 wrote to me in 2020 "I do not know as much as Joachim Denner and I trust his judgement."
Xenogenically : Porcine to Human - Xenogeneic Transplantation without PERV Infection: Dr Joachim Denner : discovered after five weeks of Pig to Human co-cultivation, no expression of PERV as mRNA, nor as protein, nor as viral particles were detected when analysed by Reverse transcription-polymerase chain reaction (RT-PCR)
Web: http://www.klinikum.uni-muenchen.de/SFB-TRR-127/de/members-neu/PI/Z2/DennerJoachim/index.html
Web: https://www.ncbi.nlm.nih.gov/pubmed/19034225
Xenogenically : Porcine to Human - Xenogeneic Transplantation without PERV Infection: Naoaki Sakata, MD, PhD : Fukuoka University · Department of Regenerative Medicine and Transplantation n-sakata@surg1.med.tohoku.ac.jp Encapsulated islets transplantation "Pigs not older than 21 weeks should be used to prevent viral infection", ideally 5 weeks to fetal Web: https://www.wjgnet.com/2150-5330/full/v3/i1/19.htm
Xenogenically : Porcine to Human - Xenogeneic Transplantation : A History Of Xeno Experiments / Starting clinical trials of xenotransplantation - reflections on the ethics of the early phase to long term surveillance of potential zoonosis Web: https://www.pbs.org/wgbh/pages/frontline/shows/organfarm/etc/cron.html
Web: https://www.intechopen.com/books/new-insights-into-cell-culture-technology/history-of-cell-culture
Web: https://jme.bmj.com/content/26/4/231
Web: https://www.who.int/ethics/en/ETH_Nuffiled_xenotransplantation.pdf?ua=1
Web: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1113984/
Xenogenically : Porcine to Human - Xenogeneic transplantation Web: target
Xenogenically : Porcine to Human - Point to Consider on Xenogeneic Cell-therapy medicinal product Web: https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-xenogeneic-cell-based-medicinal-products_en.pdf
Xenogenically : Porcine to Baboon - Xenomicrochimerism. Lack of cross-species transmission of porcine endogenous retrovirus in pig-to-baboon xenotransplantation with sustained depletion of anti-alphagal antibodies. Web: https://www.ncbi.nlm.nih.gov/pubmed/15818319
Xenogenically : Porcine to Human - Xenogeneic Transplantation : The Use of Animals for Organ Donors Web: https://www.ncbi.nlm.nih.gov/books/NBK232005/
Xenogenically : Porcine to Human - Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9 To date, no study has shown PERV transmission to humans in a clinical setting Web: https://science.sciencemag.org/content/357/6357/1303
Xenogenically : Porcine to Human - Making Pig-to-Human Transplantation a Clinical Reality using CRISPR-Cas9 genome editing Luhan Yang, Radcliffe Institute Web: https://www.youtube.com/watch?v=V0mvY1qPa0s
Xenogenically : Porcine to Human - Dr Stephen Badylak : Xenogeneic extracellular matrix as a scaffold for tissue reconstruction decellularisation and terminal sterilisation without significant loss of the biologic effects of the ECM Web: https://www.ncbi.nlm.nih.gov/pubmed/15157928
Xenogenically : Porcine to Human - Dr Stephen Badylak : Regenerative Medicine Possibilities and Potential at Singularity Summit 2011 Web: https://www.youtube.com/watch?time_continue=175&v=kC1MivfpT9o
Xenogenically : Porcine to Human - Dr Stephen Badylak : Jockeys finger regenerated with pig bladder dust Web: https://www.youtube.com/watch?v=wpctRD1He3Q
Xenogenically : Porcine to Human - Dr Stephen Badylak : How to Grow a New Fingertip Web: https://www.youtube.com/watch?v=DtBUM51t4iw
Xenogenically : Porcine to Human - Dr Stephen Badylak : Pig Bladder Could Be Key To Muscle Regrowth After Injury Web: https://www.youtube.com/watch?v=cZWPQIsXX7k
Xenogenically : Porcine to Human - Dr Stephen Badylak : Pigs Bladder Helps Patients Stem Cells Grow Missing Muscles Web: https://www.youtube.com/watch?v=qLVUeA1oFEk
Xenogenically : Porcine to Human - Dr Stephen Badylak Regen Med Strategies for Tissue & Organ Replacement badysx@upmc.edu Web: https://www.youtube.com/watch?v=gwR8rEcVu7c
Xenogenically : Porcine to Human - Dr Stephen Badylak : Human Tissue and Organ Repair Using Extracellular Matrix Pig Powder Web: https://owlcation.com/stem/How-Extracellular-Matrix-Powder-From-Pigs-and-Self-Donated-Blood-Stem-Cells-Create-New-Organs-and-Tissues
Xenogenically : Porcine to Human - Dr Stephen Badylak : The Clinical Effectiveness in Wound Healing With Extracellular Matrix Derived From Porcine Urinary Bladder Matrix A Case Series on Severe Chronic Wounds Web: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601863/
Xenogenically : Porcine to Human - Dr Stephen Badylak : Man Regrows Finger Tip With Pigs Bladder Web: https://humanlimbregeneration.com/man-regrows-finger-tip-with-pigs-bladder/
Xenogenically : Porcine to Human - Dr Stephen Badylak : Bladder biomechanics and the use of scaffolds for regenerative medicine in the urinary bladder Web: https://www.nature.com/articles/nrurol.2018.5?proof=true1
Xenogenically : Porcine to Human - Dr Stephen Badylak : Patients regrow muscles with pig bladder tissue Web: https://www.cbsnews.com/news/patients-regrow-muscles-with-pig-bladder-tissue/
Xenogenically : Porcine to Human - Dr Stephen Badylak : A Doctor, a Pig, and a Magical Pixie Dust That Could Regrow Fingers Web: https://www.esquire.com/news-politics/a3414/pigfinger1007/
Xenogenically : Porcine to Human - Dr Stephen Badylak : Leg Muscles Restored in Regenerative Medicine Study Web: https://www.youtube.com/watch?v=EOM4epIdw4k
Xenogenically : Porcine to Human - Dr Stephen Badylak : Limb Regeneration Web: https://www.youtube.com/watch?v=h7wIZ7k1dmM
Xenogenically : Porcine to Human - Dr Stephen Badylak : Tissue Engineering of Urinary Bladder and Urethra: Advances from Bench to Patients Web: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886608/
Xenogenically : Porcine to Human - Dr. Eugenio Rodriguez : Doctor Uses New Technology To “Re-Grow” Man’s Finger Web: https://miami.cbslocal.com/2013/09/16/s-fl-doctor-uses-new-technology-to-re-grow-mans-finger/
Xenogenically : Porcine to Human - Dr. Eugenio Rodriguez : The Regenerative Power of Pig Guts Web: https://www.discovermagazine.com/health/revisited-the-regenerative-power-of-pig-guts#.XMVOcJx7lhE
Xenogenically : Porcine to Human : Research Advancements in Porcine Derived Mesenchymal Stem Cells. Web: https://www.ncbi.nlm.nih.gov/pubmed/26201864
Xenogenically : Porcine to Human : Domestic pig in human medical applications Web: https://en.wikipedia.org/wiki/Domestic_pig#In_human_medical_applications
Xenogenically : Porcine to Human - Human versus porcine mesenchymal stromal cells: phenotype, differentiation potential, immunomodulation and cardiac improvement after transplantation Web: https://www.ncbi.nlm.nih.gov/pubmed/21973026
Xenogenically : Porcine to Human - Pig bladder holds healing promise: study Web: https://www.mcknights.com/news/pig-bladder-holds-healing-promise-study/
Xenogenically : Science with Stephanie : Pig 101 Dissection Web: https://www.youtube.com/watch?v=CVAzz5PZ13o
Xenogenically : Sheep to Human : Sheep Cytokines tablet for Arthritis USD 199.95 (30 Capsules): Sheep Placenta Extract. Have no antigens so not recognised as foreign by the host body. No side effects occur short or long term usage because the bio-molecules are metabolised, degenerated, & excreted via the same pathways as endogenous products.These young stem cells, which are functionally organ specific but not species specific, imprint their vigor upon old, tired, & degenerating cells, stimulating them to function with renewed efficiency. The organ/ tissue itself then retains its vigor & vitality.For arthritic hand, the stem cells can regenerate cartilages & develop new blood vessels, thus improving function & reducing pain. freeconsultation@stemcelltherapyplus.com; order@sci-therapy.com Web: http://www.stemcelltherapyplus.com/about/
Xenogenically : Human to Cat (or Dog) : Human derived GDF11 subcutaneous injection for Cat (or Dog) - medicine online for self-experimentation (Age reversal)
Web: https://www.youtube.com/watch?v=Oe9mDFRJFuk
Web: http://www.buckylabs.com/products/
Xenogenically : Human to Rat : Human Fat-Derived Mesenchymal Stem Cells Xenogenically Implanted in a Rat Model Show Enhanced New Bone Formation in Maxillary Alveolar Tooth Defects Web: https://www.hindawi.com/journals/sci/2020/8142938/
Xenogenically : Human to Mouse : Xenogeneic Transplantation of Human Placenta-Derived Mesenchymal Stem Cells Alleviates Renal Injury and Reduces Inflammation in a Mouse Model of Lupus Nephritis

Video Above shows Human to Mouse injection of Mesenchymal stem cells cured Multiple Sclerosis completely in 2 weeks
Web: https://www.hindawi.com/journals/bmri/2019/9370919/
Xenogenically : Human to Mouse : Survival of human mesenchymal stromal cells from bone marrow and adipose tissue after xenogenic transplantation in immunocompetent mice Web: https://www.sciencedirect.com/science/article/abs/pii/S1465324908702330
Xenogenically : Xenogeneic cell therapy : A novel potential therapeutic option for cancers by restoring tissue function, repairing cancer wound and reviving anti-tumor immune responses Web: https://cancerci.biomedcentral.com/articles/10.1186/s12935-018-0501-7
Xenogenically : Efficacy and biodistribution of autologous, allogeneic, and xenogeneic adipose mesenchymal stem cells on osteoarthritis Web: https://www.oarsijournal.com/article/S1063-4584(17)30779-3/fulltext
Xenogenically : Stem cell applications in disease Web: target
Xenogenically : Delray Medical Center Dr. Eugenio Rodriguez Web: https://www.delraymedicalctr.com/services/wound-care
Xenogenically : Understanding the role of mesenchymal stem cells in urinary bladder regeneration- a preclinical study on a porcine model Web: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260700/
Xenogenically : The Current Use of Stem Cells in Bladder Tissue Regeneration and Bioengineering Web: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423492/
Exosomes : International Society for Extracellular Vesicles Web: https://isev.org/
Exosomes : "Clinam" European Foundation for Clinical Nanomedicine / Microvesicles Prof. Dr. Raymond M. Schiffelers, Laboratory of Clinical Chemistry & Hematology, University Medical Center, Utrecht (NL) Web: https://clinam.org/what-who.html
Web: https://www.youtube.com/watch?v=sO01xWT9ltA
Exosomes : Direct Biologics Web: https://directbiologics.com
Exosomes : EVO Cell Therapy Program kiran.pal@evo-ffm.de Web: https://evobeverlyhills.com/portfolio-item/exosomes/
Exosomes : Dr. Margaret Coutts " Exosomes:New Paradigm In Regenerative Medicine" Exosomes do not make genetic changes with what they fuse with Web: https://www.youtube.com/watch?v=4PpC_bW7Xrw
Exosomes : Joy Wellness Partners info@joywellnesspartners.com Web: https://joywellnesspartners.com/
Exosomes : Rucker Integrative Medicine info@ruckerozonedoc.com Web: https://ruckerozonedoc.com/
Exosomes : Holistic Hormone Solutions Web: http://holistichormonesolutions.com
Exosomes : Regenerative Solutions of NJ info@StemCellCenterofNJ.com Web: https://regenerativesolutionsnj.com
Exosomes : Recharge Biomedical - Dr. Ed Park, MD, MPH (Exosomes) drpark@rechargebiomedical.com Web: http://www.rechargebiomedical.com/
Exosomes : Kimera Labs - Dr. Duncan Ross (Exosomes) info@kimeralabs.com Quotes "Nobody in the world really knows what is on the surface of an Exosome, every lipid vesicle that is 100 nm is an Exosome". Chart Messenger RNA Sequencing of Exosomes Video Young exosomes


Web: https://kimeralabs.com/about/
Web: https://youtu.be/ssFbYlRWqg8?t=1971
Exosomes : Cytokines for Arthritis: The Institute of Regenerative Medicine - Dr. Joseph Purita, Jared Kahn jkahn@stcell.com Web: https://stemcellorthopedic.com/learn-more/faq/adult-pluripotent-stem-cells/
Biomedical Gerontology : Dr. Aubrey de Grey on Radical Life Extension (Longevity Escape Velocity), intervention using Regenerative Therapy (preventative geriatric medicine, gene editing, chronic diseases of age, cell based therapies, tissue regeneration, endocrinology and deoxyribonucleic acid sequencing) aubrey@sens.org Web: https://www.youtube.com/watch?v=xB2LfJjAI9o
Web: https://www.sens.org/
Biomedical Gerontology : Sierra Sciences, LLC. - Dr. Bill Andrews curing human aging & chronic disease, telomere shortening was the reason for the Hayflick limit (number of times a normal human cell population will divide before cell division stops) bandrews@sierasci.com, info@defytime.com
Web: https://www.sierrasci.com/
Web: https://www.youtube.com/watch?v=Tx9yG6iTROQ
Web: https://defytime.com/
Biomedical Gerontology : Calico A research and development company whose mission is to harness advanced technologies to increase our understanding of the biology that controls lifespan Web: https://www.calicolabs.com/
Biomedical Gerontology : Biomedical Research and Longevity Society, Inc. (BRLS) formerly known as Life Extension Foundation, Inc., is one of the world’s leading providers of financial support for otherwise unfunded research in the areas of cryobiology, parabiosis, interventive gerontology and cryonics. info@brls.org Web: https://www.brlsociety.org/
Biomedical Gerontology : Human Longevity Inc.'s goal is to build the world's most comprehensive database on human genotypes and phenotypes, and then subject it to machine learning so that it can help develop new ways to fight diseases associated with aging Web: https://www.humanlongevity.com/
Biomedical Gerontology : Rejuvenate Bio - George Church's lab at Harvard Medical School treating aging and age-related diseases afflicting animals, such as MVD info@egenesisbio.com Web: https://www.rejuvenatebio.com/ourteam / https://www.egenesisbio.com/
Placenta : Dreambody Clinic - Lyophilised Placenta Injection (freeze dried placenta ,containg nutrients and minerals. injected subcutaneous. Parts of China and Russia have been drying placenta from live births and then cutting into the fathers abdomen and inserting the dried placenta for health benefits for hundreds of years and it has a solid track record of working. The placenta is cleaned and then lyophilised, which means freeze dried under special conditions for a sterile and easy way to get these nutrients.) info@dreambodyclinic.net Web: http://dreambody.clinic/
Placenta : Cord blood banking
Web: https://hospital.blood.co.uk/patient-services/stem-cells/cord-blood-banking/
Placenta : Biovault Family Web: https://biovaultfamily.com/
Placenta : People eat placentas Web: https://www.bbc.co.uk/news/uk-england-27307476
Placenta : Mothers Choose to Eat Their Placentas Web: https://www.theatlantic.com/health/archive/2013/03/why-some-mothers-choose-to-eat-their-placentas/273988/
Placenta : What cultures eat the placenta after birth Web: https://www.answers.com/Q/What_cultures_eat_the_placenta_after_birth
Placenta : Next Biosciences Web: https://nextbio.co.za/netcells/
Placenta : Cells4Life Group LLP Web: https://cells4life.com/cord-blood-banking-overview/about-cord-tissue/
Placenta : NHSBT Web: https://www.nhsbt.nhs.uk/contact-us/
Placenta : The Mariposa Medispa, Mexico Web: http://www.mariposamedispa.com/stemcell.html
Mesenchymal stem cells : Allogeneic Cell Therapy - Side effects of cells which are genetically dissimilar and supposedly immunologically incompatible. Dr. Neil Riordan, Mel Gibson patient.
Web: https://www.youtube.com/watch?v=IfJbnnSlewA
Mesenchymal stem cells : G. Rasul Chaudhry, PhD, Professor - Department of Biological Sciences Web: https://chaudhryoakland.wixsite.com/home
Mesenchymal stem cells : Magellan Stem Cells Web: http://www.magellanstemcells.com.au/
Mesenchymal stem cells : Stem Cell Institute - Dr. Neil Riordan Web: https://www.cellmedicine.com/
Mesenchymal stem cells : Stem Cells Transplant Institute Web: https://stemcellstransplantinstitute.com/
Mesenchymal stem cells : lntegra Medical Center Web: https://stemcellsdr.com/
Mesenchymal stem cells : Darshini Kuruppu Web: https://www.researchgate.net/profile/Darshini_Kuruppu
Mesenchymal stem cells : Center for Stem Cell Therapeutics and Imaging (CSTI) Web: http://csti.bwh.harvard.edu/team
Mesenchymal stem cells : Health & Wellness Bazaar Web: https://hwbazaar.com/treatment/joint-cartilage-restoration/?gclid=EAIaIQobChMIprLT69nP3wIVz73tCh08vwL1EAAYAiAAEgLwUvD_BwE
Mesenchymal stem cells : GIOSTAR MEXICO Web: https://docs.google.com/forms/d/e/1FAIpQLSe5TleB3BhFh4N0jtIBkzITePMSSvXIItt6qCtr8s8GB4BwoA/viewform?c=0&w=1
Mesenchymal stem cells : Could a Pill Help Us Regrow Limbs Web: https://www.youtube.com/watch?v=eKgKBz2TGow
Mesenchymal stem cells : Regen Lab - Dott. Alessandro Di Petrillo - PRP, Cellular matrix and fat grafting Web: https://www.youtube.com/watch?v=M8BnhqJ0lg0
Mesenchymal stem cells : Stem cells being used to cure back pain Web: https://www.youtube.com/watch?v=vFMgTr9x-m8
Mesenchymal stem cells : Swiss Medica clinic - Stem cell treatment Web: https://swissmedica.startstemcells.com/
Mesenchymal stem cells : Isolation and multipotential differentiation of mesenchymal stromal cell ‑ like progenitor cells from human bladder Web: https://www.spandidos-publications.com/10.3892/mmr.2018.9646?text=fulltext
Mesenchymal stem cells : Mesenchymal stromal cells - Modulate the molecular pattern of healing process in tissue engineered urinary bladder: the microarray data Web: https://stemcellres.biomedcentral.com/articles/10.1186/s13287-019-1266-1
Mesenchymal stem cells : Dr Jesse Karmazin, MD - Ambrosia (Young Blood Plasma - extracorporeal apheresis parabiosis)
Web: https://www.ambrosiaplasma.com/


Contact us by phone e-mail for any research question

Web: www.printernational.co.uk/stemcell ~ Sitemap ~ Tel: **** ~ Fax: **** ~ E-mail: Stem Cell Contact